[카테고리:] Weekly Paper Selections – WPS

1. Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology | Nature Genetics Druggability? 2. Next-generation data filtering in the genomics era | Nature Reviews Genetics 3. Synthetic surrogates improve power for genome-wide association studies of partially missing phenotypes in population biobanks | Nature Genetics Biobank imputation and enhancement 4….

1. LINE-1 transcription activates long-range gene expression | Nature Genetics … L1s can physically contact their distal target genes, with these interactions becoming stronger upon L1 activation and weaker when L1 is silenced. 2. Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction | Nature Genetics we identified…

1. Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution | Nature Genetics 2. Mapping model units to visual neurons reveals population code for social behaviour | Nature 3. Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens | Nature Biotechnology 4. Mapping medically relevant RNA isoform diversity…