[WPS] 2024.10 W5 | Nature genetics

두 달 정도 가까이 쉬었더니 볼 논문들이 너무나 많다.

따라서 이번엔 저널을 나눠서 정리했고, 이번 게시물에서는 Nature Genetics에서 8-10월에 나온 논문들 중 관심이 가는 논문들이다.

1. Obesity-dependent selection of driver mutations in cancer | Nature Genetics

2. Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries | Nature Genetics

3. Base editing screens define the genetic landscape of cancer drug resistance mechanisms | Nature Genetics

4. Mapping extrachromosomal DNA amplifications during cancer progression | Nature Genetics

5. GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia | Nature Genetics

6. Population-specific putative causal variants shape quantitative traits | Nature Genetics

7. Valid inference for machine learning-assisted genome-wide association studies | Nature Genetics

8. Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome | Nature Genetics

9. Identifying genetic variants that influence the abundance of cell states in single-cell data | Nature Genetics

10. Integration of variant annotations using deep set networks boosts rare variant association testing | Nature Genetics

11. Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study | Nature Genetics

12. Spatial transcriptomic analysis of primary and metastatic pancreatic cancers highlights tumor microenvironmental heterogeneity | Nature Genetics

13. Interpreting cis-regulatory interactions from large-scale deep neural networks | Nature Genetics

14. Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank | Nature Genetics

15. Global impact of unproductive splicing on human gene expression | Nature Genetics

16. An integrated single-cell reference atlas of the human endometrium | Nature Genetics

17. Genetic factors associated with reasons for clinical trial stoppage | Nature Genetics