[WPS] 2024.11 W5

15/12/2024

1. Study design features increase replicability in brain-wide association studies – Nature

… Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association studies are explored.

2. https://www.cell.com/cell/fulltext/S0092-8674(24)01272-8

3. https://www.cell.com/cell/fulltext/S0092-8674(24)01201-7

ST + Aging

4. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012490

Conditional probabilistic diffusion model driven synthetic radiogenomic applications in breast cancer

Author summary Breast cancer (BC) is known for its diverse characteristics, which makes it crucial for early detection and personalized treatment. Combining medical images with genomics provides a fresh approach to studying this diversity, leading to the emergence of a new field called radiogenomics…

journals.plos.org

5. https://www.nature.com/articles/s41587-024-02463-1

Recovery of biological signals lost in single-cell batch integration with CellANOVA – Nature Biotechnology

A statistical framework quantifies single-cell batch variation and recovers meaningful biological signals.

6. https://www.nature.com/articles/s41587-024-02475-x

Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling – Nature Biotechnology

MultiPerturb-seq profiles gene expression and chromatin accessibility in single-cell pooled CRISPR screen.

Massive single-cell perturbation

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